Tilman Hackeng (1962) studied chemistry with major biochemistry at the University of Utrecht, The Netherlands. He obtained his Ph.D. with Prof. Bouma at the same University in 1993 on studying protein C/protein S anticoagulant activities on endothelial cells. Shortly after, he left for The Scripps Research Institute, La Jolla, CA, USA, were he worked in the laboratories of Profs. Griffin (Molecular & Experimental Medicine) and Kent (Chemistry). In 1998 he returned to the Netherlands as a Research Fellow of the Royal Netherlands Academy of Arts and Sciences (KNAW) at the Department of Biochemistry with Prof. Rosing at the Cardiovascular Research Institute of the University Maastricht (CARIM). In 2001 he was awarded a senior researcher status and fellowship from the KNAW, followed by a VIDI personal grant from the Netherlands Organisation for Scientific Research in 2002.
Currently, he is head of the Department of Biochemistry and director of CARIM. His group studies the anticoagulant protein C/protein S/TFPI pathways and applies total chemical protein synthesis to structure-function analysis of coagulation proteins. In addition his group designs and synthesizes peptide/protein-based contrast agents for targeted molecular imaging of thrombotic disease. He has published 156 Wi-1 papers with an average impact factor of 7.3 and an h-index of 42 (WoS).
He is section editor at Thrombosis & Haemostasis, editorial board member at Thrombosis Journal, and reviewer at more than 20 international peer reviewed journals on thrombosis and haemostasis, biochemistry, and chemistry. As a member of professional organisations he is involved in the International Society on Thrombosis and Haemostasis as co-chair of the SSC Plasma Coagulation Inhibitors from 2009-2013, as regular abstract reviewer, as member of the Local Organizing Committee ISTH 2013, and as member of the International advisory board and Scientific topic program member at ISTH 2017. In addition he is past treasurer and past president of the Netherlands Society on Thrombosis and Hemostasis (NVTH). He is member of the American Chemical Society and the Royal Netherlands Society of Chemistry, and is elected member of the Royal Netherlands Society of Sciences and Humanities (KHMW) since 2014.
Supervisor of project 9 – Molecular and drug design to detect and target vascular microcalcification
